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Hyaluronic Acid

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Introduction:

Product Name

Hyaluronic Acid

Synonyms

Sodium Hyaluronate, HA

Grade

Food and Cosmetic grade.

Appearance

White or almost white powder

CAS

9004-61-9

Molecular formula

C28H44N2O23

Molecular weight(Da)

Low, Medium, High molecular weight

Sample

Available


Pure Hyaluronic acid is a kind of acidic mucopolysaccharide, with its unique molecular structure and physicochemical properties in the body shows a variety of important physiological functions, such as lubrication of joints, regulating the permeability of the blood vessel wall, regulating proteins, water-electrolyte diffusion and functioning, and promoting trauma healing. Particularly important is that hyaluronic acid has a special water retention effect, is currently found in the natural world of the best moisturising substances, known as the ideal natural moisturising factor.


Specification:

Cosmetic grade:

Items Specifications Results
Characters White or almost white powder or grain White or almost white powder or grain
Identify
Infrared Absorption
Complied with the reference spectrum of Sodium Hyaluronate Complied with the reference spectrum of Sodium Hyaluronate
Reaction of Sodium
Positive Positive
Glucuronic Acid Content, % ≥45.0 46.20
Sodium Hyaluronate Content, % ≥93.0 95.50
Intrinsic Viscosity, dl/g Measured value 20.12
Average Molecular Weight, MDa Measured value 1.22
Transparency, % ≥99.0 99.8
Loss on drying, % ≤10.0 9.42
Absorbance ≤0.25 0.096
pH (0.1% Water Solution, 25°C) 5.0 - 8.5 6.94
Heavy Metal (In Lead), mg/kg ≤20 <20
Protein, % ≤0.05 0.042
Ignition residue, % ≤20 12.80
Bacteria Counts, CFU/g ≤100 Conform to the standard
Mold & Yeast, CFU/g ≤10 Conform to the standard
Staphylococcus Aureus/g Negative Negative
Pseudomonas aeruginosa/g Negative Negative
Conclusion Conformed to - In - house Standards


Food grade:

Items Specifications Results
Characters White or almost white powder or grain White or almost white powder or grain
Identify
Infrared Absorption
Complied with the reference spectrum of Sodium Hyaluronate Complied with the reference spectrum of Sodium Hyaluronate
Reaction of Sodium
Positive Positive
Glucuronic Acid Content, % ≥44.0 45.25
Sodium Hyaluronate Content, % ≥91.0 93.63
Intrinsic Viscosity, dl/g Measured value 19.08
Average Molecular Weight, MDa Measured value 1.14
Transparency, % ≥99.0 100.0
Moisture Content, % ≤10.0 5.70
pH (0.1% Water Solution, 25°C) 6.0 - 8.0 6.50
Heavy Metal (In Lead), mg/kg ≤10 <10
Ash Content, % ≤13 10.37
Bacteria Counts, CFU/g ≤100 Conform to the standard
Mold & Yeast, CFU/g ≤50 Conform to the standard
Staphylococcus Aureus/g Negative Negative
Salmonella/25g Negative Negative
Coliform group, CFU/g Negative Negative
Viable Hemolytical Streptococci/25g Negative Negative
Conclusion Conformed to - In - house Standards


Function and Application:

1. Hyaluronic acid has an excellent affinity for water and reorganises water within the tissue to better carry loads or lubricate.Hyaluronic acid raw material powder can be used for skin care.

2. Hyaluronic acid can fold to form a three-dimensional network that produces physiological effects. These include generating fluid resistance, maintaining water balance and internal environmental stability in the body, affecting solubility, spatial configuration, chemical balance and systemic osmotic pressure of biomolecules, blocking pathogen playback, and directing the deposition of secretory substances from collagen fibres.

3. In cartilage, the proteoglycan aggregates formed by hyaluronic acid and chondroitin sulphate and keratin sulphate are structurally important components of the organisation.

4. Sodium hyaluronate powder can be used as a natural moisturising agent in cosmetics, as a lubricant in surgery and as a vitreous replacement agent in ophthalmic surgery. Hyaluronic acid food grade can be used as raw material for health care products.With the advancement of technology, bulk hyaluronic acid is also available at very affordable prices.


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