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Introduction：
Product Name | Hydroxypropyl Betadex |
Appearance | White or almost white powder. |
CAS | 7585-39-9 |
Molecular formula | C42H70O35 |
Molecular Weight | 1134.99 |
Sample | Available |
Hydroxypropyl Betadex, is an organic compound, white to light yellow powder, slightly pectin characteristic aroma, taste slightly sweet and slightly sour. Hydroxypropyl Betadex can be dissolved in water, insoluble in ethanol and other organic solvents. Betacyclodextrin as a new type of pharmaceutical excipients are mainly used to increase the stability of the drug to prevent the oxidation and decomposition of the drug, used to increase the solubility of the drug and the degree of bioavailability, for the reduction of the drug's toxicity and side effects. It is used to mask the bad taste and odor of drugs. Betacyclodextrin is mainly used in food manufacturing to eliminate bad taste, to improve the stability of spices and flavors as well as pigments, and to enhance the emulsification ability and moisture-proofing ability. Hydroxypropyl Betadex powder improves the texture of food, and it is a good stabilizer and flavour correcting agent for pharmaceutical food and cosmetic manufacturing industry.
Specification:
Items | Specifications | Results | |
Appearance | White or almost white, amorphous or crystalline powder. Freely soluble in water and in propylene glycol. | Conform | |
Identification | IR | Same absorption bands as USP Hydroxypropyl Betadex RS | Conform |
Clarity of solution | Positive | ||
Molar substitution | 0.40-1.50 | 0.67 | |
Betadex | ≤1.5% | 0.36% | |
Propylene glycol | ≤2.5% | 0.07% | |
Any other single impurity | ≤0.25% | Not detected | |
Total impurities excluding betadex and propylene glycol | ≤1.0% | Not detected | |
Propylene oxide | ≤0.0001% | 0.000001% | |
Loss on drying | ≤10.0% | 3.7% | |
Clarity of solution | 1.0g/2ml water solution is clear and transparent | Conform | |
Conductivity | ≤200μS/cm | 70μS/cm | |
The total aerobic microbial count | ≤1000cfu/g | <10cfu/g | |
The total combined molds and yeasts count | ≤100cfu/g | <10cfu/g | |
Function and Application:
1. Hydroxypropyl Betadex can be used as drug carrier, stabilizer, encapsulant, etc., to increase drug stability, prevent drug oxidation and decomposition, improve drug solubility and bioavailability, make insoluble drugs better dissolved and absorbed, reduce drug toxicity and side-effects, mask drug odor and taste, and improve the taste of drugs.
2. Betadex can be used as food thickener, can improve the texture of food, also can be used as antioxidant, adsorption of oxygen, reduce the rate of redox reaction in food, prevent food spoilage due to oxidation, prolong the shelf life of food; also can be used as an emulsifier, to increase the stability of the oil-water emulsion, so that the food in the oil and water to mix better!
3. Betadex powder can increase the stability and effectiveness of cosmetic products, as a carrier of flavor substances and aroma substances, make the fragrance of cosmetics more durable, and at the same time help to maintain skin moisture and promote the absorption of active ingredients.
Introduction：
Product Name | Hydroxypropyl Betadex |
Appearance | White or almost white powder. |
CAS | 7585-39-9 |
Molecular formula | C42H70O35 |
Molecular Weight | 1134.99 |
Sample | Available |
Hydroxypropyl Betadex, is an organic compound, white to light yellow powder, slightly pectin characteristic aroma, taste slightly sweet and slightly sour. Hydroxypropyl Betadex can be dissolved in water, insoluble in ethanol and other organic solvents. Betacyclodextrin as a new type of pharmaceutical excipients are mainly used to increase the stability of the drug to prevent the oxidation and decomposition of the drug, used to increase the solubility of the drug and the degree of bioavailability, for the reduction of the drug's toxicity and side effects. It is used to mask the bad taste and odor of drugs. Betacyclodextrin is mainly used in food manufacturing to eliminate bad taste, to improve the stability of spices and flavors as well as pigments, and to enhance the emulsification ability and moisture-proofing ability. Hydroxypropyl Betadex powder improves the texture of food, and it is a good stabilizer and flavour correcting agent for pharmaceutical food and cosmetic manufacturing industry.
Specification:
Items | Specifications | Results | |
Appearance | White or almost white, amorphous or crystalline powder. Freely soluble in water and in propylene glycol. | Conform | |
Identification | IR | Same absorption bands as USP Hydroxypropyl Betadex RS | Conform |
Clarity of solution | Positive | ||
Molar substitution | 0.40-1.50 | 0.67 | |
Betadex | ≤1.5% | 0.36% | |
Propylene glycol | ≤2.5% | 0.07% | |
Any other single impurity | ≤0.25% | Not detected | |
Total impurities excluding betadex and propylene glycol | ≤1.0% | Not detected | |
Propylene oxide | ≤0.0001% | 0.000001% | |
Loss on drying | ≤10.0% | 3.7% | |
Clarity of solution | 1.0g/2ml water solution is clear and transparent | Conform | |
Conductivity | ≤200μS/cm | 70μS/cm | |
The total aerobic microbial count | ≤1000cfu/g | <10cfu/g | |
The total combined molds and yeasts count | ≤100cfu/g | <10cfu/g | |
Function and Application:
1. Hydroxypropyl Betadex can be used as drug carrier, stabilizer, encapsulant, etc., to increase drug stability, prevent drug oxidation and decomposition, improve drug solubility and bioavailability, make insoluble drugs better dissolved and absorbed, reduce drug toxicity and side-effects, mask drug odor and taste, and improve the taste of drugs.
2. Betadex can be used as food thickener, can improve the texture of food, also can be used as antioxidant, adsorption of oxygen, reduce the rate of redox reaction in food, prevent food spoilage due to oxidation, prolong the shelf life of food; also can be used as an emulsifier, to increase the stability of the oil-water emulsion, so that the food in the oil and water to mix better!
3. Betadex powder can increase the stability and effectiveness of cosmetic products, as a carrier of flavor substances and aroma substances, make the fragrance of cosmetics more durable, and at the same time help to maintain skin moisture and promote the absorption of active ingredients.