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L-Hydroxyproline

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Introduction:

Product Name

L-Hydroxyproline

Appearance

White crystals or crystalline powder

CAS

51-35-4

Molecular formula

C5H9NO3

Molecular Weight  

131.13

Purity

99.9%min

Sample

Available

Hydroxyproline (HYP) is one of the subamino acids, a non-essential amino acid, is one of the main components of collagen tissue, and is a unique amino acid in collagen, accounting for about 13% of the total collagen amino acids. Proline is a cyclic subamino acid, and L-proline is one of the twenty amino acids used by the body to synthesize protein. Collagen is the most abundant protein in the body, accounting for about 1/3 of the total protein in the human body. using the characteristic that hydroxyproline has the highest content in collagen, the measurement of hydroxyproline in blood and urine can be used to understand the decomposition and metabolism of collagen in the body, which can be used as an indicator of the decomposition of connective tissue. Many diseases can be accompanied by changes in collagen metabolism and cause changes in blood, urine and tissue hydroxyproline content.


Specification:

Test items

AJI92

Test results

Test method

Description

White crystals or crystalline powder

Conforms

Visual

Identification

Ninhydrin color experiment

Conforms

Visual

Specific rotation

-74.0°~ -77.0°

-75.5°

AJI Test 1

Transmittance

≥95.0%

97.5%

AJI Test 2

Chloride

≤0.02%

<0.02%

AJI Test 3

Ammonium salt

≤0.02%

<0.02%

AJI Test 4

Sulfate

≤0.02%

<0.02%

AJI Test 5

Iron

≤10ppm

<10ppm

AJI Test 6

Heavy metals(Pb)

≤10ppm

<10ppm

AJI Test 7

Arsenic

≤1pm

<1ppm

AJI Test 8

Other Amino Acids

Chromatographically not detectable    

Not detected

AJI Test 9

Loss on drying

≤0.20%

0.06%

AJI Test 11

Residue on ignition

≤0.10%

0.05%

AJI Test 13

Assay

98.5~101.0%

99.3%

AJI Test 14

pH

5.0~6.5

5.4

AJI Test 33


Function and Application:

1. Hydroxyproline is used as an intermediate in the synthesis of drugs for the preparation of a number of biologically active compounds. It is also used in nutraceuticals, often in conjunction with other nutrients such as vitamin C, to promote collagen synthesis, which helps maintain healthy skin, joints and bones.

2. Due to the important role of L-hydroxyproline in collagen, it is widely used in cosmetics such as creams and serums. The addition of hydroxyproline can help the skin retain moisture, increase skin elasticity, reduce wrinkles, and play a role in beauty and skin care.

3. L-Hydroxyproline can be used as a food additive to improve the texture and taste of food and enhance the stability of food. In some functional foods, L-hydroxyproline powder is also often added to improve the nutritional value of the product.


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