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Introduction：
Product Name | Troxerutin |
Appearance | Yellowish-green,Crystalline powder |
CAS | 7085-55-4 |
Molecular formula | C33H42O19 |
Molecular Weight | 742.68 |
Purity | 95.0%min Troxerutin |
Sample | Available |
Troxerutin is a mixture of hydroxyethyl rutin obtained by hydroxyethylation of rutin, yellow, yellow-green or light brown-yellow powder, odorless and slightly salty taste, moisture-attracting, and its hydrolysis of the main products for the chrysoside.
Troxerutin is made of rutin by hydroxyethylation, semi-synthetic flavonoid compounds. It can inhibit erythrocyte and platelet agglutination, at the same time can increase the blood oxygen content, improve microcirculation, promote the formation of new blood vessels, is a better treatment of occlusive cerebrovascular drugs to protect the endothelial cells, treatment of acute ischemic brain injury. Troxerutin also has anti-radiation damage, anti-inflammation, anti-allergy, anti-ulcer and other effects, is the main component of Vibramycin, troxerutin powder often made into tablets and injections to use.
Specification:
Items | Specifications | Results | Test Method |
Appearance Identification
Particle size Solubility: in water in ethanol (96 per cent) in methylene chloride Composition principal peak One peak Other each peak Ethylene oxide Residual solvents (Methanol) Heavy metals -Arsenic -Mercury -Cadmium -Lead Bulk Density Tapped Density Residue on ignition Loss on drying Assay | Yellowish-green,Crystallinepowder, hygroscopic A. IR B. Examine the chromatograms obtained in the test of composition. 100% pass through 80 mesh
Soluble freely Soluble slightly Practically insoluble
≥80.0% ≤10.0% ≤5.0% ≤1.0ppm
≤3000ppm ≤20ppm ≤1.0ppm ≤0.1ppm ≤1.0ppm ≤3.0ppm ≥0.40gm/cc ≥0.60gm/cc ≤0.4% ≤5.0% 95.0% —105.0% | Complies Complies Complies
Complies
Complies Complies Complies
86.1% 4.5% 2.8% <1.0ppm
<3000ppm <20ppm <1.0ppm <0.1ppm <1.0ppm <3.0ppm 0.43gm/cc 0.62gm/cc 0.27% 2.91% 99.62% | Visual IR HPLC
EP10.0
Visual Visual Visual
HPLC HPLC HPLC HPGC
HPGC Visual Colorimetry ICP-MS ICP-MS ICP-MS ICP-MS CP2015 CP2015 EP10.0 105℃/4h UV |
Microbiological test: Total aerobic microbial count Total yeasts and moulds count E.Coli Salmonella Coliforms |
≤1000cfu/g ≤100cfu/g Negative Negative ≤10cfu/g |
<10 cfu/g <10 cfu/g Negative Negative <10cfu/g |
EP10.0 EP10.0 EP10.0 EP10.0 EP10.0 |
Function and Application:
1. Troxerutin can inhibit platelet aggregation and has the effect of preventing thrombosis.
2. Troxerutin can slow down the vascular damage caused by skin irritation, increase capillary resistance, reduce capillary permeability, and can prevent edema caused by elevated vascular permeability. It has significant protective effect on acute ischemic brain injury.
3. Troxerutin is a water-soluble derivative of rutin, which has similar pharmacological effects with rutin, and has higher biological utilization, and has significant central and peripheral analgesic effects. Rutin powder is often made into nutritional supplements such as rutin capsules.
Introduction：
Product Name | Troxerutin |
Appearance | Yellowish-green,Crystalline powder |
CAS | 7085-55-4 |
Molecular formula | C33H42O19 |
Molecular Weight | 742.68 |
Purity | 95.0%min Troxerutin |
Sample | Available |
Troxerutin is a mixture of hydroxyethyl rutin obtained by hydroxyethylation of rutin, yellow, yellow-green or light brown-yellow powder, odorless and slightly salty taste, moisture-attracting, and its hydrolysis of the main products for the chrysoside.
Troxerutin is made of rutin by hydroxyethylation, semi-synthetic flavonoid compounds. It can inhibit erythrocyte and platelet agglutination, at the same time can increase the blood oxygen content, improve microcirculation, promote the formation of new blood vessels, is a better treatment of occlusive cerebrovascular drugs to protect the endothelial cells, treatment of acute ischemic brain injury. Troxerutin also has anti-radiation damage, anti-inflammation, anti-allergy, anti-ulcer and other effects, is the main component of Vibramycin, troxerutin powder often made into tablets and injections to use.
Specification:
Items | Specifications | Results | Test Method |
Appearance Identification
Particle size Solubility: in water in ethanol (96 per cent) in methylene chloride Composition principal peak One peak Other each peak Ethylene oxide Residual solvents (Methanol) Heavy metals -Arsenic -Mercury -Cadmium -Lead Bulk Density Tapped Density Residue on ignition Loss on drying Assay | Yellowish-green,Crystallinepowder, hygroscopic A. IR B. Examine the chromatograms obtained in the test of composition. 100% pass through 80 mesh
Soluble freely Soluble slightly Practically insoluble
≥80.0% ≤10.0% ≤5.0% ≤1.0ppm
≤3000ppm ≤20ppm ≤1.0ppm ≤0.1ppm ≤1.0ppm ≤3.0ppm ≥0.40gm/cc ≥0.60gm/cc ≤0.4% ≤5.0% 95.0% —105.0% | Complies Complies Complies
Complies
Complies Complies Complies
86.1% 4.5% 2.8% <1.0ppm
<3000ppm <20ppm <1.0ppm <0.1ppm <1.0ppm <3.0ppm 0.43gm/cc 0.62gm/cc 0.27% 2.91% 99.62% | Visual IR HPLC
EP10.0
Visual Visual Visual
HPLC HPLC HPLC HPGC
HPGC Visual Colorimetry ICP-MS ICP-MS ICP-MS ICP-MS CP2015 CP2015 EP10.0 105℃/4h UV |
Microbiological test: Total aerobic microbial count Total yeasts and moulds count E.Coli Salmonella Coliforms |
≤1000cfu/g ≤100cfu/g Negative Negative ≤10cfu/g |
<10 cfu/g <10 cfu/g Negative Negative <10cfu/g |
EP10.0 EP10.0 EP10.0 EP10.0 EP10.0 |
Function and Application:
1. Troxerutin can inhibit platelet aggregation and has the effect of preventing thrombosis.
2. Troxerutin can slow down the vascular damage caused by skin irritation, increase capillary resistance, reduce capillary permeability, and can prevent edema caused by elevated vascular permeability. It has significant protective effect on acute ischemic brain injury.
3. Troxerutin is a water-soluble derivative of rutin, which has similar pharmacological effects with rutin, and has higher biological utilization, and has significant central and peripheral analgesic effects. Rutin powder is often made into nutritional supplements such as rutin capsules.